THPO polyclonal antibody
产品名称： THPO polyclonal antibody
英文名称： THPO polyclonal antibody
产品编号： PAB2956
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of THPO.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to amino acids 307-337 at C-terminus of human THPO.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Congenital amegakaryocytic thrombocytopenia-3 novel c-MPL mutations and their phenotypic correlations.
Steinberg O, Gilad G, Dgany O, Krasnov T, Zoldan M, Laor R, Kapelushnik J, Gabriel H, Churi C, Stein J, Yaniv I, Tamary H.J Pediatr Hematol Oncol. 2007 Dec;29(12):822-5.
- 2.
- A new role of thrombopoietin enhancing ex vivo expansion of endothelial precursor cells derived from AC133-positive cells.
Kanayasu-Toyoda T, Ishii-Watabe A, Suzuki T, Oshizawa T, Yamaguchi T.J Biol Chem. 2007 Nov 16;282(46):33507-14. Epub 2007 Sep 7.
- 3.
- Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats.
Baker JE, Su J, Hsu A, Shi Y, Zhao M, Strande JL, Fu X, Xu H, Eis A, Komorowski R, Jensen ES, Tweddell JS, Rafiee P, Gross GJ.Cardiovasc Res. 2008 Jan;77(1):44-53. Epub 2007 Sep 22.
- Entrez GeneID:
- 7066
- Protein Accession#:
- NP_000451;P40225
- Gene Name:
- THPO
- Gene Alias:
- MGC163194,MGDF,MKCSF,ML,MPLLG,TPO
- Gene Description:
- thrombopoietin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. [provided by RefSeq
- Other Designations:
- MPL ligand,c-mpl ligand,megakaryocyte colony-stimulating factor,megakaryocyte growth and development factor,megakaryocyte stimulating factor,myeloproliferative leukemia virus oncogene ligand,thrombopoietin nirs variant 1
- Gene Pathway
- Related Disease
- Atherosclerosis
- Cardiovascular Diseases
- Chorioamnionitis
- Diabetes Mellitus, Type 2
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Myocardial Infarction
- Obstetric Labor, Premature
- Pre-Eclampsia
- Premature Birth
- Thrombocythemia, Hemorrhagic
- Werner syndrome